UCP2 muscle gene transfer modifies mitochondrial membrane potential
نویسندگان
چکیده
منابع مشابه
The mitochondrial membrane potential and Ca2+ oscillations in smooth muscle.
Ca2+ uptake by mitochondria might both modulate the cytosolic Ca2+ concentration ([Ca2+]c) and depolarize the mitochondrial membrane potential (delta Psi m) to limit ATP production. To investigate how physiological Ca2+ signaling might affect energy production, delta Psi m was examined during Ca2+ oscillations in smooth muscle cells. In single, voltage-clamped smooth muscle cells, inhibition of...
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In humans the skeletal musculature can constitute over 50% of the body mass, and a range of anatomical, physiological and cellular features makes this tissue an attractive candidate for gene transfer procedures designed to augment normal gene function, express heterologous therapeutic products or immunize the host organism. Under normal conditions, skeletal myofibres are stable post-mitotic cel...
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c p p r p q m Rest and stress myocardial perfusion imaging, described nearly 4 decades ago (1), is now performed in 9 million people annually in the United States (2). The procedure provides clinically useful data regardless of whether the tracer is a monovalent cation such as potassium, thallium, or rubidium; a highly diffusible agent such as O-labeled water; an amino acid precursor such as am...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2001
ISSN: 0307-0565,1476-5497
DOI: 10.1038/sj.ijo.0801484